Non-static framework for understanding adaptive designs: an ethical justification in paediatric trials

Many drugs used in paediatric medicine are off-label. There is a rising call for the use of adaptive clinical trial designs (ADs) in responding to the need for safe and effective drugs given their potential to offer efficiency and cost-effective benefits compared with traditional clinical trials. AD...

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Detalles Bibliográficos
Autores principales: Afolabi, Michael OS, Kelly, Lauren E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626916/
https://www.ncbi.nlm.nih.gov/pubmed/34362828
http://dx.doi.org/10.1136/medethics-2021-107263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626916/
https://www.ncbi.nlm.nih.gov/pubmed/34362828
http://dx.doi.org/10.1136/medethics-2021-107263

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