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Non-static framework for understanding adaptive designs: an ethical justification in paediatric trials
Many drugs used in paediatric medicine are off-label. There is a rising call for the use of adaptive clinical trial designs (ADs) in responding to the need for safe and effective drugs given their potential to offer efficiency and cost-effective benefits compared with traditional clinical trials. AD...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BMJ Publishing Group
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626916/ https://www.ncbi.nlm.nih.gov/pubmed/34362828 http://dx.doi.org/10.1136/medethics-2021-107263 |