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The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling

CX3CL1, also known as fractalkine, is best known for its signaling activity through interactions with its cognate receptor CX3CR1. However, its intrinsic function that is independent of interaction with CX3CR1 remains to be fully understood. We demonstrate that the intracellular domain of CX3CL1 (CX...

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Detalles Bibliográficos
Autores principales:	Gayen, Manoshi, Benoit, Marc R., Fan, Qingyuan, Hudobenko, Jacob, Yan, Riqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626938/ https://www.ncbi.nlm.nih.gov/pubmed/36162508 http://dx.doi.org/10.1016/j.jbc.2022.102532

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