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Treg-Dominant Tumor Microenvironment Is Responsible for Hyperprogressive Disease after PD-1 Blockade Therapy

Programmed cell death 1 (PD-1) blockade therapy can result in dramatic responses in some patients with cancer. However, about 15% of patients receiving PD-1 blockade therapy experience rapid tumor progression, a phenomenon termed “hyperprogressive disease” (HPD). The mechanism(s) underlying HPD has...

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Detalles Bibliográficos
Autores principales:	Wakiyama, Hiroaki, Kato, Takuya, Furusawa, Aki, Okada, Ryuhei, Inagaki, Fuyuki, Furumoto, Hideyuki, Fukushima, Hiroshi, Okuyama, Shuhei, Choyke, Peter L., Kobayashi, Hisataka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627263/ https://www.ncbi.nlm.nih.gov/pubmed/36169564 http://dx.doi.org/10.1158/2326-6066.CIR-22-0041

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