Selective D3 receptor antagonism modulates neural response during negative emotional processing in substance dependence

INTRODUCTION: Negative affective states contribute to the chronic-relapsing nature of addiction. Mesolimbic dopamine D3 receptors are well placed to modulate emotion and are dysregulated in substance dependence. Selective antagonists might restore dopaminergic hypofunction, thus representing a poten...

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Detalles Bibliográficos
Autores principales: Vamvakopoulou, Ioanna A., Fonville, Leon, Hayes, Alexandra, McGonigle, John, Elliott, Rebecca, Ersche, Karen D., Flechais, Remy, Orban, Csaba, Murphy, Anna, Smith, Dana G., Suckling, John, Taylor, Eleanor M., Deakin, Bill, Robbins, Trevor W., Nutt, David J., Lingford-Hughes, Anne R., Paterson, Louise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627287/
https://www.ncbi.nlm.nih.gov/pubmed/36339857
http://dx.doi.org/10.3389/fpsyt.2022.998844

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