Fasting inhibits excitatory synaptic input on paraventricular oxytocin neurons via neuropeptide Y and Y1 receptor, inducing rebound hyperphagia, and weight gain

Fasting with varying intensities is used to treat obesity-related diseases. Re-feeding after fasting exhibits hyperphagia and often rebound weight gain. However, the mechanisms underlying the hyperphagia and rebound remain elusive. Here we show that 24 h food restriction (24 h FR) and milder 50% FR,...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Suyama, Shigetomo, Lee, Samantha A., Ueta, Yoichi, Seino, Yutaka, Sharp, Geoffrey W. G., Yada, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627337/
https://www.ncbi.nlm.nih.gov/pubmed/36337662
http://dx.doi.org/10.3389/fnut.2022.994827

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