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Parthanatos participates in glutamate‐mediated HT22 cell injury and hippocampal neuronal death in kainic acid‐induced status epilepticus rats

AIMS: Epileptic seizures or status epilepticus (SE) can cause hippocampal neuronal death, which has detrimental effects. Parthanatos, a new form of programmed cell death, is characterized by hyperactivation of poly (ADP‐ribose) polymerase‐1 (PARP‐1), excessive synthesis of poly ADP‐ribose polymer, m...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Zhang, Wuqiong, Ge, Pengfei, Yu, Miaomiao, Meng, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627358/
https://www.ncbi.nlm.nih.gov/pubmed/35909335
http://dx.doi.org/10.1111/cns.13934