Lomitapide ameliorates middle cerebral artery occlusion‐induced cerebral ischemia/reperfusion injury by promoting neuronal autophagy and inhibiting microglial migration

AIMS: Stroke has a high incidence and is a disabling condition that can lead to severe cognitive, motor, and sensory dysfunction. In this study, we employed a drug repurposing strategy to investigate the neuroprotective effect of lomitapide on focal ischemic brain injury and explore its potential me...

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Detalles Bibliográficos
Autores principales: Zheng, Yangmin, Hu, Yue, Han, Ziping, Yan, Feng, Zhang, Sijia, Yang, Zhenhong, Zhao, Fangfang, Li, Lingzhi, Fan, Junfen, Wang, Rongliang, Luo, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627359/
https://www.ncbi.nlm.nih.gov/pubmed/36052650
http://dx.doi.org/10.1111/cns.13961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627359/
https://www.ncbi.nlm.nih.gov/pubmed/36052650
http://dx.doi.org/10.1111/cns.13961

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