TFG mutation induces haploinsufficiency and drives axonal Charcot–Marie–Tooth disease by causing neurite degeneration

AIMS: TFG‐related axonal Charcot–Marie–Tooth (CMT) disease is a late‐onset, autosomal dominant, hereditary motor, and sensory neuropathy characterized by slowly progressive weakness and atrophy of the distal muscles. The objective of this study was to determine the common pathogenic mechanism of TFG...

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Detalles Bibliográficos
Autores principales: Chen, Xihui, Liu, Fangfang, Chen, Kun, Wang, Yufeng, Yin, Anan, Kang, Xiaowei, Yang, Shanming, Zhao, Hanwen, Dong, Songqi, Li, Yunqing, Chen, Jing, Wu, Yuanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627391/
https://www.ncbi.nlm.nih.gov/pubmed/35986567
http://dx.doi.org/10.1111/cns.13943

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