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Experimental hyperoxia (O(2) supersaturation) reveals a gill diffusion limitation of maximum aerobic performance in fish
Several studies have demonstrated that hyperoxia increases the maximal O(2) consumption rate (ṀO(2max)) in fish, but exactly how this occurs remains to be explained. Here, we tested the hypothesis that hyperoxia improves arterial oxygenation in rainbow trout during exhaustive exercise. We demonstrat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627442/ https://www.ncbi.nlm.nih.gov/pubmed/36321431 http://dx.doi.org/10.1098/rsbl.2022.0401 |
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author | McArley, T. J. Morgenroth, D. Zena, L. A. Ekström, A. T. Sandblom, E. |
author_facet | McArley, T. J. Morgenroth, D. Zena, L. A. Ekström, A. T. Sandblom, E. |
author_sort | McArley, T. J. |
collection | PubMed |
description | Several studies have demonstrated that hyperoxia increases the maximal O(2) consumption rate (ṀO(2max)) in fish, but exactly how this occurs remains to be explained. Here, we tested the hypothesis that hyperoxia improves arterial oxygenation in rainbow trout during exhaustive exercise. We demonstrate a 35% higher ṀO(2max) in hyperoxia (200% air saturation) relative to normoxia, which was achieved through a combined 15% increase in cardiac output due to elevated peak heart rate, and a 19% increase of the arterial–venous (A-V) O(2) content difference. While arterial O(2) partial pressure (PaO(2)) and O(2) saturation of haemoglobin declined post-exhaustive exercise in normoxia, this did not occur in hyperoxia. This protective effect of hyperoxia on arterial oxygenation led to a 22% higher arterial O(2) content post-exhaustive exercise, thereby allowing a higher A-V O(2) content difference. These findings indicate that ṀO(2max) is gill diffusion limited in exhaustively exercised rainbow trout. Moreover, as previous studies in salmonids have demonstrated collapsing PaO(2) in normoxia at maximal swimming speed and at acutely high temperatures, a diffusion limitation may constrain ṀO(2) in other situations eliciting peak metabolic demand. These findings, along with the fact that hyperoxia increases ṀO(2max) in several other fishes, suggest that gill diffusion limitations of ṀO(2max) may be widespread in fishes. |
format | Online Article Text |
id | pubmed-9627442 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-96274422022-11-14 Experimental hyperoxia (O(2) supersaturation) reveals a gill diffusion limitation of maximum aerobic performance in fish McArley, T. J. Morgenroth, D. Zena, L. A. Ekström, A. T. Sandblom, E. Biol Lett Physiology Several studies have demonstrated that hyperoxia increases the maximal O(2) consumption rate (ṀO(2max)) in fish, but exactly how this occurs remains to be explained. Here, we tested the hypothesis that hyperoxia improves arterial oxygenation in rainbow trout during exhaustive exercise. We demonstrate a 35% higher ṀO(2max) in hyperoxia (200% air saturation) relative to normoxia, which was achieved through a combined 15% increase in cardiac output due to elevated peak heart rate, and a 19% increase of the arterial–venous (A-V) O(2) content difference. While arterial O(2) partial pressure (PaO(2)) and O(2) saturation of haemoglobin declined post-exhaustive exercise in normoxia, this did not occur in hyperoxia. This protective effect of hyperoxia on arterial oxygenation led to a 22% higher arterial O(2) content post-exhaustive exercise, thereby allowing a higher A-V O(2) content difference. These findings indicate that ṀO(2max) is gill diffusion limited in exhaustively exercised rainbow trout. Moreover, as previous studies in salmonids have demonstrated collapsing PaO(2) in normoxia at maximal swimming speed and at acutely high temperatures, a diffusion limitation may constrain ṀO(2) in other situations eliciting peak metabolic demand. These findings, along with the fact that hyperoxia increases ṀO(2max) in several other fishes, suggest that gill diffusion limitations of ṀO(2max) may be widespread in fishes. The Royal Society 2022-11-02 /pmc/articles/PMC9627442/ /pubmed/36321431 http://dx.doi.org/10.1098/rsbl.2022.0401 Text en © 2022 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Physiology McArley, T. J. Morgenroth, D. Zena, L. A. Ekström, A. T. Sandblom, E. Experimental hyperoxia (O(2) supersaturation) reveals a gill diffusion limitation of maximum aerobic performance in fish |
title | Experimental hyperoxia (O(2) supersaturation) reveals a gill diffusion limitation of maximum aerobic performance in fish |
title_full | Experimental hyperoxia (O(2) supersaturation) reveals a gill diffusion limitation of maximum aerobic performance in fish |
title_fullStr | Experimental hyperoxia (O(2) supersaturation) reveals a gill diffusion limitation of maximum aerobic performance in fish |
title_full_unstemmed | Experimental hyperoxia (O(2) supersaturation) reveals a gill diffusion limitation of maximum aerobic performance in fish |
title_short | Experimental hyperoxia (O(2) supersaturation) reveals a gill diffusion limitation of maximum aerobic performance in fish |
title_sort | experimental hyperoxia (o(2) supersaturation) reveals a gill diffusion limitation of maximum aerobic performance in fish |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627442/ https://www.ncbi.nlm.nih.gov/pubmed/36321431 http://dx.doi.org/10.1098/rsbl.2022.0401 |
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