Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells

Better understanding on interactions between SARS‐CoV‐2 and host cells should help to identify host factors that may be targetable to combat infection and COVID‐19 pathology. To this end, we have conducted a genome‐wide CRISPR/Cas9‐based loss‐of‐function screen in human lung cancer cells infected wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ugalde, Alejandro P, Bretones, Gabriel, Rodríguez, David, Quesada, Víctor, Llorente, Francisco, Fernández‐Delgado, Raúl, Jiménez‐Clavero, Miguel Ángel, Vázquez, Jesús, Calvo, Enrique, Tamargo‐Gómez, Isaac, Mariño, Guillermo, Roiz‐Valle, David, Maeso, Daniel, Araujo‐Voces, Miguel, Español, Yaiza, Barceló, Carles, Freije, José MP, López‐Soto, Alejandro, López‐Otín, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627672/
https://www.ncbi.nlm.nih.gov/pubmed/36124427
http://dx.doi.org/10.15252/embj.2022110727

Ejemplares similares

Ejemplares similares