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B7-H3 targeted CAR-T cells show highly efficient anti-tumor function against osteosarcoma both in vitro and in vivo

BACKGROUND: Osteosarcoma (OS) mainly happens in children and youths. Surgery, radiotherapy and chemotherapy are the common therapies for osteosarcoma treatment but all their anti-tumor effects are limited. In recent years, a new cellular therapy, CAR-T, a cellular immunotherapy with genetically engi...

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Detalles Bibliográficos
Autores principales:	Zhang, Qian, Zhang, Zhiqiang, Liu, Guodi, Li, Dehua, Gu, Zhangjie, Zhang, Linsong, Pan, Yingjiao, Cui, Xingbing, Wang, Lu, Liu, Guoping, Tian, Xiaoli, Zhang, Ziming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628043/ https://www.ncbi.nlm.nih.gov/pubmed/36320072 http://dx.doi.org/10.1186/s12885-022-10229-8

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