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PSTPIP2 regulates synovial macrophages polarization and dynamics via ERβ in the joint microenvironment

BACKGROUND: The cytoskeletal protein, PSTPIP2, is associated with inflammation and is predominantly expressed in macrophages. Previous data have shown that PSTPIP2 inhibits articular bone damage in arthritic rats. The aim of this study is to explore the molecular mechanism of PSTPIP2’s resistance to...

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Detalles Bibliográficos
Autores principales: Yao, Yao, Cai, Xiaoyu, Zhang, Meng, Zhang, Xiao, Ren, Fujia, Zheng, Yan, Fei, Weidong, Zhao, Mengdan, Zheng, Caihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628044/
https://www.ncbi.nlm.nih.gov/pubmed/36324152
http://dx.doi.org/10.1186/s13075-022-02939-y