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Conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study

BACKGROUND: Surgical treatment for recurrent bone tumors in the extremities still presents a challenge. This study was designed to evaluate the clinical value of microwave ablation in the treatment of recurrent bone tumors. METHODS: We present 15 patients who underwent microwave ablation for recurre...

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Autores principales: Zheng, Kai, Yu, Xiu-chun, Xu, Ming, Wang, Jing-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628094/
https://www.ncbi.nlm.nih.gov/pubmed/36320002
http://dx.doi.org/10.1186/s12885-022-10233-y
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author Zheng, Kai
Yu, Xiu-chun
Xu, Ming
Wang, Jing-ming
author_facet Zheng, Kai
Yu, Xiu-chun
Xu, Ming
Wang, Jing-ming
author_sort Zheng, Kai
collection PubMed
description BACKGROUND: Surgical treatment for recurrent bone tumors in the extremities still presents a challenge. This study was designed to evaluate the clinical value of microwave ablation in the treatment of recurrent bone tumors. METHODS: We present 15 patients who underwent microwave ablation for recurrent bone tumors during the last 7 years. The following parameters were analyzed for outcome evaluation: general condition, surgical complications, local disease control, overall survival, and functional score measured using the Musculoskeletal Tumor Society (MSTS) 93 scoring system. RESULTS: Percutaneous microwave ablation in one patient with osteoid osteoma and another with bone metastasis resulted in postoperative pain relief. Thirteen patients received intraoperative microwave ablation before curettage or resection, including those with giant cell tumors of bone (6), chondroblastoma (2), osteosarcoma (2), undifferentiated sarcoma (1), and bone metastases (2). All patients achieved reasonable local tumor control in the mean follow-up of 29.9 months. The functional score was 24.1 for the 15 patients 6 months after the operation. Four patients had tumor metastasis and died, whereas 3 patients with tumors survived, and the remaining 8 patients without the disease survived. CONCLUSIONS: Microwave ablation represents an optional method for local control in treating recurrent bone tumors in the extremities.
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spelling pubmed-96280942022-11-03 Conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study Zheng, Kai Yu, Xiu-chun Xu, Ming Wang, Jing-ming BMC Cancer Research BACKGROUND: Surgical treatment for recurrent bone tumors in the extremities still presents a challenge. This study was designed to evaluate the clinical value of microwave ablation in the treatment of recurrent bone tumors. METHODS: We present 15 patients who underwent microwave ablation for recurrent bone tumors during the last 7 years. The following parameters were analyzed for outcome evaluation: general condition, surgical complications, local disease control, overall survival, and functional score measured using the Musculoskeletal Tumor Society (MSTS) 93 scoring system. RESULTS: Percutaneous microwave ablation in one patient with osteoid osteoma and another with bone metastasis resulted in postoperative pain relief. Thirteen patients received intraoperative microwave ablation before curettage or resection, including those with giant cell tumors of bone (6), chondroblastoma (2), osteosarcoma (2), undifferentiated sarcoma (1), and bone metastases (2). All patients achieved reasonable local tumor control in the mean follow-up of 29.9 months. The functional score was 24.1 for the 15 patients 6 months after the operation. Four patients had tumor metastasis and died, whereas 3 patients with tumors survived, and the remaining 8 patients without the disease survived. CONCLUSIONS: Microwave ablation represents an optional method for local control in treating recurrent bone tumors in the extremities. BioMed Central 2022-11-02 /pmc/articles/PMC9628094/ /pubmed/36320002 http://dx.doi.org/10.1186/s12885-022-10233-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zheng, Kai
Yu, Xiu-chun
Xu, Ming
Wang, Jing-ming
Conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study
title Conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study
title_full Conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study
title_fullStr Conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study
title_full_unstemmed Conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study
title_short Conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study
title_sort conservative surgery with microwave ablation for recurrent bone tumor in the extremities: a single-center study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628094/
https://www.ncbi.nlm.nih.gov/pubmed/36320002
http://dx.doi.org/10.1186/s12885-022-10233-y
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