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Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost
BACKGROUND: Drug non-adherence is assumed to play an important role in development of hypertensive urgency, which is a common health problem resulting in frequent emergency department admissions and thus increased healthcare spending wastage. The objective of this study is to assess the rate of non-...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628133/ https://www.ncbi.nlm.nih.gov/pubmed/36319947 http://dx.doi.org/10.1186/s12872-022-02907-z |
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author | Abbas, Hanine Hallit, Souheil Kurdi, Mazen Karam, Rita |
author_facet | Abbas, Hanine Hallit, Souheil Kurdi, Mazen Karam, Rita |
author_sort | Abbas, Hanine |
collection | PubMed |
description | BACKGROUND: Drug non-adherence is assumed to play an important role in development of hypertensive urgency, which is a common health problem resulting in frequent emergency department admissions and thus increased healthcare spending wastage. The objective of this study is to assess the rate of non-adherence to antihypertensives and to evaluate influencing factors predicting this behavior in Lebanese hypertensive adults. In addition, this study aim to estimate the cost of hospitalization for hypertensive urgency covered by the Ministry of Public Health in patients’ non-adherent to their antihypertensives. METHODS: A multi-methods approach is used comprising a cross-sectional study, additionally to an observational, retrospective, cost of illness study. A cross-sectional questionnaire based study is conducted from May to Dec, 2019 to address the study objective. Using the Ministry of Public Health hospitalization data during 2019, the cost of hospitalization for hypertensive urgency is assessed. Multivariable analysis is performed to calculate the adjusted odd ratios by fitting a logistic regression model. RESULTS: The cross-sectional study includes 494 participants and shows that 43.0% of patients hospitalized and covered by the Ministry of Public Health are non-adherent. The univariate regression model shows that adherence to antihypertensive medications is significantly associated with age (p-value = 0.005) and follow-up visits (p-value = 0.046). The odds of adherence for participants earning more than USD 2000 was 3.27 times that for those who earn less than USD 1000 (p = 0.026). The estimated cost of hospitalization for non-adherent patients is USD 452,353 in 2019. CONCLUSION: Non-adherence associated hospitalization costs represents a financial burden to Lebanese health system. |
format | Online Article Text |
id | pubmed-9628133 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-96281332022-11-03 Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost Abbas, Hanine Hallit, Souheil Kurdi, Mazen Karam, Rita BMC Cardiovasc Disord Research BACKGROUND: Drug non-adherence is assumed to play an important role in development of hypertensive urgency, which is a common health problem resulting in frequent emergency department admissions and thus increased healthcare spending wastage. The objective of this study is to assess the rate of non-adherence to antihypertensives and to evaluate influencing factors predicting this behavior in Lebanese hypertensive adults. In addition, this study aim to estimate the cost of hospitalization for hypertensive urgency covered by the Ministry of Public Health in patients’ non-adherent to their antihypertensives. METHODS: A multi-methods approach is used comprising a cross-sectional study, additionally to an observational, retrospective, cost of illness study. A cross-sectional questionnaire based study is conducted from May to Dec, 2019 to address the study objective. Using the Ministry of Public Health hospitalization data during 2019, the cost of hospitalization for hypertensive urgency is assessed. Multivariable analysis is performed to calculate the adjusted odd ratios by fitting a logistic regression model. RESULTS: The cross-sectional study includes 494 participants and shows that 43.0% of patients hospitalized and covered by the Ministry of Public Health are non-adherent. The univariate regression model shows that adherence to antihypertensive medications is significantly associated with age (p-value = 0.005) and follow-up visits (p-value = 0.046). The odds of adherence for participants earning more than USD 2000 was 3.27 times that for those who earn less than USD 1000 (p = 0.026). The estimated cost of hospitalization for non-adherent patients is USD 452,353 in 2019. CONCLUSION: Non-adherence associated hospitalization costs represents a financial burden to Lebanese health system. BioMed Central 2022-11-01 /pmc/articles/PMC9628133/ /pubmed/36319947 http://dx.doi.org/10.1186/s12872-022-02907-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Abbas, Hanine Hallit, Souheil Kurdi, Mazen Karam, Rita Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost |
title | Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost |
title_full | Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost |
title_fullStr | Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost |
title_full_unstemmed | Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost |
title_short | Non-adherence to antihypertensive medications in Lebanese adults hospitalized for hypertensive urgency and its cost |
title_sort | non-adherence to antihypertensive medications in lebanese adults hospitalized for hypertensive urgency and its cost |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628133/ https://www.ncbi.nlm.nih.gov/pubmed/36319947 http://dx.doi.org/10.1186/s12872-022-02907-z |
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