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Modeling COVID-19 infection in high-risk settings and low-risk settings
In this research paper we present a mathematical model for COVID-19 in high-risk settings and low-risk settings which might be infection dynamics between hotspots and less risky communities. The main idea was to couple the SIR model with alternating risk levels from the two different settings high a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628209/ https://www.ncbi.nlm.nih.gov/pubmed/36345348 http://dx.doi.org/10.1016/j.pce.2022.103288 |
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author | Ndlovu, Meshach Mpofu, Mqhelewenkosi A. Moyo, Rodwell G. |
author_facet | Ndlovu, Meshach Mpofu, Mqhelewenkosi A. Moyo, Rodwell G. |
author_sort | Ndlovu, Meshach |
collection | PubMed |
description | In this research paper we present a mathematical model for COVID-19 in high-risk settings and low-risk settings which might be infection dynamics between hotspots and less risky communities. The main idea was to couple the SIR model with alternating risk levels from the two different settings high and low-risk settings. Therefore, building from this model we partition the infected class into two categories, the symptomatic and the asymptomatic. Using this approach we simulated COVID-19 dynamics in low and high-risk settings with auto-switching risk settings. Again, the model was analyzed using both analytic methods and numerical methods. The results of this study suggest that switching risk levels in different settings plays a pivotal role in COVID-19 progression dynamics. Hence, population reaction time to adhere to preventative measures and interventions ought to be implemented with flash speed targeting first the high-risk setting while containing the dynamics in low-risk settings. |
format | Online Article Text |
id | pubmed-9628209 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96282092022-11-03 Modeling COVID-19 infection in high-risk settings and low-risk settings Ndlovu, Meshach Mpofu, Mqhelewenkosi A. Moyo, Rodwell G. Phys Chem Earth (2002) Article In this research paper we present a mathematical model for COVID-19 in high-risk settings and low-risk settings which might be infection dynamics between hotspots and less risky communities. The main idea was to couple the SIR model with alternating risk levels from the two different settings high and low-risk settings. Therefore, building from this model we partition the infected class into two categories, the symptomatic and the asymptomatic. Using this approach we simulated COVID-19 dynamics in low and high-risk settings with auto-switching risk settings. Again, the model was analyzed using both analytic methods and numerical methods. The results of this study suggest that switching risk levels in different settings plays a pivotal role in COVID-19 progression dynamics. Hence, population reaction time to adhere to preventative measures and interventions ought to be implemented with flash speed targeting first the high-risk setting while containing the dynamics in low-risk settings. Elsevier Ltd. 2022-12 2022-11-02 /pmc/articles/PMC9628209/ /pubmed/36345348 http://dx.doi.org/10.1016/j.pce.2022.103288 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Ndlovu, Meshach Mpofu, Mqhelewenkosi A. Moyo, Rodwell G. Modeling COVID-19 infection in high-risk settings and low-risk settings |
title | Modeling COVID-19 infection in high-risk settings and low-risk settings |
title_full | Modeling COVID-19 infection in high-risk settings and low-risk settings |
title_fullStr | Modeling COVID-19 infection in high-risk settings and low-risk settings |
title_full_unstemmed | Modeling COVID-19 infection in high-risk settings and low-risk settings |
title_short | Modeling COVID-19 infection in high-risk settings and low-risk settings |
title_sort | modeling covid-19 infection in high-risk settings and low-risk settings |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628209/ https://www.ncbi.nlm.nih.gov/pubmed/36345348 http://dx.doi.org/10.1016/j.pce.2022.103288 |
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