Cargando…

Modeling COVID-19 infection in high-risk settings and low-risk settings

In this research paper we present a mathematical model for COVID-19 in high-risk settings and low-risk settings which might be infection dynamics between hotspots and less risky communities. The main idea was to couple the SIR model with alternating risk levels from the two different settings high a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ndlovu, Meshach, Mpofu, Mqhelewenkosi A., Moyo, Rodwell G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628209/
https://www.ncbi.nlm.nih.gov/pubmed/36345348
http://dx.doi.org/10.1016/j.pce.2022.103288
_version_ 1784823146238443520
author Ndlovu, Meshach
Mpofu, Mqhelewenkosi A.
Moyo, Rodwell G.
author_facet Ndlovu, Meshach
Mpofu, Mqhelewenkosi A.
Moyo, Rodwell G.
author_sort Ndlovu, Meshach
collection PubMed
description In this research paper we present a mathematical model for COVID-19 in high-risk settings and low-risk settings which might be infection dynamics between hotspots and less risky communities. The main idea was to couple the SIR model with alternating risk levels from the two different settings high and low-risk settings. Therefore, building from this model we partition the infected class into two categories, the symptomatic and the asymptomatic. Using this approach we simulated COVID-19 dynamics in low and high-risk settings with auto-switching risk settings. Again, the model was analyzed using both analytic methods and numerical methods. The results of this study suggest that switching risk levels in different settings plays a pivotal role in COVID-19 progression dynamics. Hence, population reaction time to adhere to preventative measures and interventions ought to be implemented with flash speed targeting first the high-risk setting while containing the dynamics in low-risk settings.
format Online
Article
Text
id pubmed-9628209
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-96282092022-11-03 Modeling COVID-19 infection in high-risk settings and low-risk settings Ndlovu, Meshach Mpofu, Mqhelewenkosi A. Moyo, Rodwell G. Phys Chem Earth (2002) Article In this research paper we present a mathematical model for COVID-19 in high-risk settings and low-risk settings which might be infection dynamics between hotspots and less risky communities. The main idea was to couple the SIR model with alternating risk levels from the two different settings high and low-risk settings. Therefore, building from this model we partition the infected class into two categories, the symptomatic and the asymptomatic. Using this approach we simulated COVID-19 dynamics in low and high-risk settings with auto-switching risk settings. Again, the model was analyzed using both analytic methods and numerical methods. The results of this study suggest that switching risk levels in different settings plays a pivotal role in COVID-19 progression dynamics. Hence, population reaction time to adhere to preventative measures and interventions ought to be implemented with flash speed targeting first the high-risk setting while containing the dynamics in low-risk settings. Elsevier Ltd. 2022-12 2022-11-02 /pmc/articles/PMC9628209/ /pubmed/36345348 http://dx.doi.org/10.1016/j.pce.2022.103288 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Ndlovu, Meshach
Mpofu, Mqhelewenkosi A.
Moyo, Rodwell G.
Modeling COVID-19 infection in high-risk settings and low-risk settings
title Modeling COVID-19 infection in high-risk settings and low-risk settings
title_full Modeling COVID-19 infection in high-risk settings and low-risk settings
title_fullStr Modeling COVID-19 infection in high-risk settings and low-risk settings
title_full_unstemmed Modeling COVID-19 infection in high-risk settings and low-risk settings
title_short Modeling COVID-19 infection in high-risk settings and low-risk settings
title_sort modeling covid-19 infection in high-risk settings and low-risk settings
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628209/
https://www.ncbi.nlm.nih.gov/pubmed/36345348
http://dx.doi.org/10.1016/j.pce.2022.103288
work_keys_str_mv AT ndlovumeshach modelingcovid19infectioninhighrisksettingsandlowrisksettings
AT mpofumqhelewenkosia modelingcovid19infectioninhighrisksettingsandlowrisksettings
AT moyorodwellg modelingcovid19infectioninhighrisksettingsandlowrisksettings