Spatial transcriptomics of the lacrimal gland features macrophage activity and epithelium metabolism as key alterations during chronic inflammation

The lacrimal gland (LG) is an exocrine gland that produces the watery part of the tear film that lubricates the ocular surface. Chronic inflammation, such as Sjögren’s syndrome (SS), is one of the leading causes of aqueous-deficiency dry eye (ADDE) disease worldwide. In this study we analyzed the ch...

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Detalles Bibliográficos
Autores principales: Mauduit, Olivier, Delcroix, Vanessa, Umazume, Takeshi, de Paiva, Cintia S., Dartt, Darlene A., Makarenkova, Helen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628215/
https://www.ncbi.nlm.nih.gov/pubmed/36341342
http://dx.doi.org/10.3389/fimmu.2022.1011125

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