The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes

The blood–brain barrier (BBB) is a kind of filter, highly selective in relation to various types of substances. The BBB supports the immune status of the brain and is an important regulator of neuroimmune interactions. Some of the molecular and cellular features of the BBB, as well as the five main...

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Detalles Bibliográficos
Autores principales: Dyatlova, A. S., Novikova, N. S., Yushkov, B. G., Korneva, E. A., Chereshnev, V. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628516/
https://www.ncbi.nlm.nih.gov/pubmed/36340326
http://dx.doi.org/10.1134/S1019331622050100
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author Dyatlova, A. S.
Novikova, N. S.
Yushkov, B. G.
Korneva, E. A.
Chereshnev, V. A.
author_facet Dyatlova, A. S.
Novikova, N. S.
Yushkov, B. G.
Korneva, E. A.
Chereshnev, V. A.
author_sort Dyatlova, A. S.
collection PubMed
description The blood–brain barrier (BBB) is a kind of filter, highly selective in relation to various types of substances. The BBB supports the immune status of the brain and is an important regulator of neuroimmune interactions. Some of the molecular and cellular features of the BBB, as well as the five main pathways of neuroimmune communication mediated by the BBB, are analyzed in this article. The functions of the BBB in neuroimmune interactions in various diseases are discussed: multiple sclerosis and Alzheimer’s and Parkinson’s diseases. The latest data on BBB dysfunction in COVID-19 coronavirus infection caused by the SARS-CoV-2 virus are considered.
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spelling pubmed-96285162022-11-02 The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes Dyatlova, A. S. Novikova, N. S. Yushkov, B. G. Korneva, E. A. Chereshnev, V. A. Her Russ Acad Sci Review The blood–brain barrier (BBB) is a kind of filter, highly selective in relation to various types of substances. The BBB supports the immune status of the brain and is an important regulator of neuroimmune interactions. Some of the molecular and cellular features of the BBB, as well as the five main pathways of neuroimmune communication mediated by the BBB, are analyzed in this article. The functions of the BBB in neuroimmune interactions in various diseases are discussed: multiple sclerosis and Alzheimer’s and Parkinson’s diseases. The latest data on BBB dysfunction in COVID-19 coronavirus infection caused by the SARS-CoV-2 virus are considered. Pleiades Publishing 2022-11-02 2022 /pmc/articles/PMC9628516/ /pubmed/36340326 http://dx.doi.org/10.1134/S1019331622050100 Text en © Pleiades Publishing, Ltd. 2022, ISSN 1019-3316, Herald of the Russian Academy of Sciences, 2022, Vol. 92, No. 5, pp. 590–599. © Pleiades Publishing, Ltd., 2022.Russian Text © The Author(s), 2022, published in Vestnik Rossiiskoi Akademii Nauk, 2022, Vol. 92, No. 10, pp. 950–960. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Dyatlova, A. S.
Novikova, N. S.
Yushkov, B. G.
Korneva, E. A.
Chereshnev, V. A.
The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes
title The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes
title_full The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes
title_fullStr The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes
title_full_unstemmed The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes
title_short The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes
title_sort blood−brain barrier in neuroimmune interactions and pathological processes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628516/
https://www.ncbi.nlm.nih.gov/pubmed/36340326
http://dx.doi.org/10.1134/S1019331622050100
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