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MiR-125b-5p modulates the function of regulatory T cells in tumor microenvironment by targeting TNFR2
BACKGROUND: Tumor necrosis factor receptor type 2 (TNFR2) is primarily expressed by CD4(+)FoxP3(+) regulatory T cells (Tregs), especially those present in tumor microenvironment. There is compelling evidence that TNFR2 plays a crucial role in the activation, expansion, and phenotypic stability of Tr...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628696/ https://www.ncbi.nlm.nih.gov/pubmed/36319063 http://dx.doi.org/10.1136/jitc-2022-005241 |