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MiR-125b-5p modulates the function of regulatory T cells in tumor microenvironment by targeting TNFR2

BACKGROUND: Tumor necrosis factor receptor type 2 (TNFR2) is primarily expressed by CD4(+)FoxP3(+) regulatory T cells (Tregs), especially those present in tumor microenvironment. There is compelling evidence that TNFR2 plays a crucial role in the activation, expansion, and phenotypic stability of Tr...

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Detalles Bibliográficos
Autores principales:	Jiang, Mengmeng, Yang, Yang, Niu, Liling, Li, Ping, Chen, Yibo, Liao, Ping, Wang, Yifei, Zheng, Jingbin, Chen, Fengyang, He, Huanhuan, Li, Hui, Chen, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628696/ https://www.ncbi.nlm.nih.gov/pubmed/36319063 http://dx.doi.org/10.1136/jitc-2022-005241

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