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Novel plant-derived recombinant human interferons with broad spectrum antiviral activity

Type I interferons (IFNs) are potent mediators of the innate immune response to viral infection. IFNs released from infected cells bind to a receptor (IFNAR) on neighboring cells, triggering signaling cascades that limit further infection. Subtle variations in amino acids can alter IFNAR binding and...

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Detalles Bibliográficos
Autores principales:	Koehler, Jeffrey W., Dupuy, Lesley C., Garrison, Aura R., Beitzel, Brett F., Richards, Michelle J., Ripoll, Daniel R., Wallqvist, Anders, Teh, Shia-Yen, Vaewhongs, Andrew A., Vojdani, Fakhrieh S., Padgett, Hal S., Schmaljohn, Connie S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628711/ https://www.ncbi.nlm.nih.gov/pubmed/22020161 http://dx.doi.org/10.1016/j.antiviral.2011.10.008

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