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Four-gene-combination DNA vaccine protects mice against a lethal vaccinia virus challenge and elicits appropriate antibody responses in nonhuman primates
Two major infectious forms of vaccinia virus (VACV) have been described: the intracellular mature virion (IMV), and the extracellular enveloped virion (EEV). Due to their stability in the environment, IMVs play a predominant role in host-to-host transmission, whereas EEVs play an important role in d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science (USA).
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628742/ https://www.ncbi.nlm.nih.gov/pubmed/12620810 http://dx.doi.org/10.1016/S0042-6822(02)00038-7 |