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Streptomyces BAC Cloning of a Large-Sized Biosynthetic Gene Cluster of NPP B1, a Potential SARS-CoV-2 RdRp Inhibitor

As valuable antibiotics, microbial natural products have been in use for decades in various fields. Among them are polyene compounds including nystatin, amphotericin, and nystatin-like Pseudonocardia polyenes (NPPs). Polyene macrolides are known to possess various biological effects, such as antifun...

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Detalles Bibliográficos
Autores principales:	Park, Ji-Hee, Park, Heung-Soon, Nah, Hee-Ju, Kang, Seung-Hoon, Choi, Si-Sun, Kim, Eung-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Microbiology and Biotechnology 2022
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628923/ https://www.ncbi.nlm.nih.gov/pubmed/35719079 http://dx.doi.org/10.4014/jmb.2205.05036

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