Deciphering and reprogramming the cyclization regioselectivity in bifurcation of indole alkaloid biosynthesis

The metabolism of monoterpene indole alkaloids (MIAs) is an outstanding example of how plants shape chemical diversity from a single precursor. Here we report the discovery of novel enzymes from the Alstonia scholaris tree, a cytochrome P450, an NADPH dependent oxidoreductase and a BAHD acyltransfer...

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Detalles Bibliográficos
Autores principales: Wang, Zhuo, Xiao, Yiren, Wu, Song, Chen, Jianghua, Li, Ang, Tatsis, Evangelos C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628931/
https://www.ncbi.nlm.nih.gov/pubmed/36349266
http://dx.doi.org/10.1039/d2sc03612f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628931/
https://www.ncbi.nlm.nih.gov/pubmed/36349266
http://dx.doi.org/10.1039/d2sc03612f

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