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DED Interaction of FADD and Caspase-8 in the Induction of Apoptotic Cell Death

Fas-associated death domain (FADD) is an adapter molecule that bridges the interaction between receptor-interacting protein 1 (RIP1) and aspartate-specific cysteine protease-8 (caspase-8). As the primary mediator of apoptotic cell death, caspase-8 has two N-terminal death-effector domains (DEDs) and...

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Detalles Bibliográficos
Autores principales: Park, Young-Hoon, Han, Chang Woo, Jeong, Mi Suk, Jang, Se Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Microbiology and Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628938/
https://www.ncbi.nlm.nih.gov/pubmed/35879276
http://dx.doi.org/10.4014/jmb.2206.06003