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Antiviral activity of cyclopentenyl nucleosides against orthopox viruses (Smallpox, monkeypox and cowpox)
An improved method for the synthesis of enantiomerically pure d-cyclopentenyl nucleosides has been accomplished and their antiviral activity against orthopox viruses have been evaluated. The key intermediate, l-cyclopent-2-enone 13 was prepared from d-ribose using a ring closing metathesis reaction...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd.
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628949/ https://www.ncbi.nlm.nih.gov/pubmed/12467606 http://dx.doi.org/10.1016/S0960-894X(02)00841-7 |