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LuxR-Type SCO6993 Negatively Regulates Antibiotic Production at the Transcriptional Stage by Binding to Promoters of Pathway-Specific Regulatory Genes in Streptomyces coelicolor

SCO6993 (606 amino acids) in Streptomyces coelicolor belongs to the large ATP-binding regulators of the LuxR family regulators having one DNA-binding motif. Our previous findings predicted that SCO6993 may suppress the production of pigmented antibiotics, actinorhodin, and undecylprodigiosin, in S....

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Detalles Bibliográficos
Autores principales:	Tsevelkhoroloo, Maral, Xiaoqiang, Li, Jin, Xue-Mei, Shin, Jung-Ho, Lee, Chang-Ro, Kang, Yup, Hong, Soon-Kwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Microbiology and Biotechnology 2022
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628970/ https://www.ncbi.nlm.nih.gov/pubmed/36116920 http://dx.doi.org/10.4014/jmb.2205.07050

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