OR16-2 Steroid Receptor Co-Activator Complexes Regulate Metabolic PFKFB Enzymes to Drive Therapy Resistant ER+ Breast Cancer

Recurrence of metastatic breast cancer stemming from acquired endocrine and chemotherapy resistance remains a health burden for women with luminal (ER+) breast cancer. ER+ tumor cells can remain viable but quiescent for years to decades. Contributing factors to metastatic spread include the survival...

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Detalles Bibliográficos
Autores principales: Benner, Elizabeth, Dos Santos, Camila, Hagen, Kyla, Lange, Carol, Ostrander, Julie, Temiz, Nuri, Trousdell, Marygrace, Truong, Thu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629109/
http://dx.doi.org/10.1210/jendso/bvac150.1821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629109/
http://dx.doi.org/10.1210/jendso/bvac150.1821

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