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OR16-2 Steroid Receptor Co-Activator Complexes Regulate Metabolic PFKFB Enzymes to Drive Therapy Resistant ER+ Breast Cancer
Recurrence of metastatic breast cancer stemming from acquired endocrine and chemotherapy resistance remains a health burden for women with luminal (ER+) breast cancer. ER+ tumor cells can remain viable but quiescent for years to decades. Contributing factors to metastatic spread include the survival...
Autores principales: | Benner, Elizabeth, Dos Santos, Camila, Hagen, Kyla, Lange, Carol, Ostrander, Julie, Temiz, Nuri, Trousdell, Marygrace, Truong, Thu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629109/ http://dx.doi.org/10.1210/jendso/bvac150.1821 |
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