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RF07 | PSUN355 Downstream Targets of the Steroidogenic Factor-1 (SF-1) Antagonist OR-449 in PDX Models of ACC

BACKGROUND: Adrenocortical cancer (ACC) is a rare endocrine malignancy frequently diagnosed at an advanced stage when prognosis is dismal. Mitotane, the only approved therapy for locally advanced or metastatic disease, is minimally effective, and recent clinical trials with multi-kinase inhibitors o...

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Detalles Bibliográficos
Autores principales:	Crowe, Paul, Fox, Ray, Tao, Haiyan, Raheja, Neil, Auchus, Richard, Houghton, Peter, Thacher, Scott
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Tumor Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629131/ http://dx.doi.org/10.1210/jendso/bvac150.1853

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