Cargando…
Licoricidin combats gastric cancer by targeting the ICMT/Ras pathway in vitro and in vivo
Licoricidin, a type of isoflavonoid, is extracted from the root of Glycyrrhiza glabra. It has been widely proven that licoricidin possesses multiple biological activities, including anti-cancer effects and a powerful antimicrobial effect against Helicobacter pylori (H. pylori). However, the exact me...
Autores principales: | Ma, Hanwei, Wu, Fahong, Bai, Yinliang, Wang, Tianwei, Ma, Shangxian, Guo, Liuqing, Liu, Guiyuan, Leng, Guangxian, Kong, Yin, Zhang, Youcheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629146/ https://www.ncbi.nlm.nih.gov/pubmed/36339587 http://dx.doi.org/10.3389/fphar.2022.972825 |
Ejemplares similares
-
lncRNA
ELFN1-AS1 promotes proliferation, migration and invasion and suppresses apoptosis in colorectal cancer cells by enhancing
G6PD activity
: lncRNA
ELFN1-AS1 promotes the progression of colorectal cancer
por: Wu, Fahong, et al.
Publicado: (2023) -
Atomic structure of the eukaryotic intramembrane Ras methyltransferase ICMT
por: Diver, Melinda M., et al.
Publicado: (2018) -
Vertical sleeve gastrectomy-derived gut metabolite licoricidin activates beige fat thermogenesis to combat obesity
por: Jin, Zhangliu, et al.
Publicado: (2023) -
NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane
por: Ahearn, Ian M, et al.
Publicado: (2021) -
PFKFB4 interacts with ICMT and activates RAS/AKT signaling-dependent cell migration in melanoma
por: Sittewelle, Méghane, et al.
Publicado: (2022)