RF19 | PSUN349 Histone Eraser and Reader Targeting Epigenetic Inhibitors Are Effective in Pancreatic Neuroendocrine Tumours

BACKGROUND: The 5-year survival for metastatic pancreatic neuroendocrine tumours (PNETs) is <50%, and current therapies are not effective. Thus, there is an unmet clinical need for new therapies for patients with PNETs. PNETs frequently have mutations in chromatin remodelling genes, including in...

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Detalles Bibliográficos
Autores principales: Carmichael, James, Escoubet, Laure, Lines, Kate, Mavrommatis, Konstantinos, Mortensen, Deborah, Thakker, Rajesh V, Thakurta, Anjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629168/
http://dx.doi.org/10.1210/jendso/bvac150.1859

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