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LBSAT142 Discovery And Characterization Of A Potent And Orally Bioavailable Parathyroid Hormone Receptor Type-1 (PTHR1) Antagonist For The Treatment Of Hypercalcemia

Hypercalcemia is a common disorder defined as a serum calcium concentration higher than the normal range of 8.5 - 10.5 mg/dL. The most common causes of hypercalcemia are over-secretion of parathyroid hormone (PTH) from one or more enlarged parathyroid glands, which can lead to primary hyperparathyro...

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Detalles Bibliográficos
Autores principales: Rico-Bautista, Elizabeth, Pontillo, Joseph, Wang, Shimiao, Antwan, Agnes S, Arroyo, Pablo, Fleck, Beth, Fowler, Melissa A, Reinhart, Greg, Johns, Michael A, Kusnetzow, Ana K, Zhu, Yun Fei, Markison, Stacy, Betz, Stephen F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629207/
http://dx.doi.org/10.1210/jendso/bvac150.309