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Thyroid-like follicular carcinoma of the kidney presenting in a 13-year-old female: a case report from Syria

Thyroid-like follicular carcinoma of the kidney (TLFCK) is a rare cancer that emerged to the medical literature only a few years ago. We present here the first case of thyroid follicular carcinoma-like renal tumor from Syria. The case presented symptomatically and was managed in our surgical unit. G...

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Autores principales: Al Mousa, Ahmad, Rahmeh, Sami, Rezkallah, Vairy, Ghabreau, Lina, Alhadid, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629467/
https://www.ncbi.nlm.nih.gov/pubmed/36348638
http://dx.doi.org/10.1093/jscr/rjac467
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author Al Mousa, Ahmad
Rahmeh, Sami
Rezkallah, Vairy
Ghabreau, Lina
Alhadid, Ibrahim
author_facet Al Mousa, Ahmad
Rahmeh, Sami
Rezkallah, Vairy
Ghabreau, Lina
Alhadid, Ibrahim
author_sort Al Mousa, Ahmad
collection PubMed
description Thyroid-like follicular carcinoma of the kidney (TLFCK) is a rare cancer that emerged to the medical literature only a few years ago. We present here the first case of thyroid follicular carcinoma-like renal tumor from Syria. The case presented symptomatically and was managed in our surgical unit. Generally, the presenting age described for the previous cases was 19–60 (mean 39.5) with only three cases with younger ages. Here in our case, the patient is only 13 years old making this only the fourth case worldwide of TLFCK in a child. The microscopic view of the tumor showed distinct thyroid features. In addition the immunohistochemical stains played the definitive role in the diagnosis. The staining for Vimentin, and CK19 were diffusively positive. CK7 was focally positive, whereas TTf1, Thyroglobulin, WT1, CD10 and EMA were negative. It is important to consider this diagnosis to spare the patient the treatment protocol of primary thyroid cancer with metastasis.
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spelling pubmed-96294672022-11-07 Thyroid-like follicular carcinoma of the kidney presenting in a 13-year-old female: a case report from Syria Al Mousa, Ahmad Rahmeh, Sami Rezkallah, Vairy Ghabreau, Lina Alhadid, Ibrahim J Surg Case Rep Case Report Thyroid-like follicular carcinoma of the kidney (TLFCK) is a rare cancer that emerged to the medical literature only a few years ago. We present here the first case of thyroid follicular carcinoma-like renal tumor from Syria. The case presented symptomatically and was managed in our surgical unit. Generally, the presenting age described for the previous cases was 19–60 (mean 39.5) with only three cases with younger ages. Here in our case, the patient is only 13 years old making this only the fourth case worldwide of TLFCK in a child. The microscopic view of the tumor showed distinct thyroid features. In addition the immunohistochemical stains played the definitive role in the diagnosis. The staining for Vimentin, and CK19 were diffusively positive. CK7 was focally positive, whereas TTf1, Thyroglobulin, WT1, CD10 and EMA were negative. It is important to consider this diagnosis to spare the patient the treatment protocol of primary thyroid cancer with metastasis. Oxford University Press 2022-10-31 /pmc/articles/PMC9629467/ /pubmed/36348638 http://dx.doi.org/10.1093/jscr/rjac467 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Al Mousa, Ahmad
Rahmeh, Sami
Rezkallah, Vairy
Ghabreau, Lina
Alhadid, Ibrahim
Thyroid-like follicular carcinoma of the kidney presenting in a 13-year-old female: a case report from Syria
title Thyroid-like follicular carcinoma of the kidney presenting in a 13-year-old female: a case report from Syria
title_full Thyroid-like follicular carcinoma of the kidney presenting in a 13-year-old female: a case report from Syria
title_fullStr Thyroid-like follicular carcinoma of the kidney presenting in a 13-year-old female: a case report from Syria
title_full_unstemmed Thyroid-like follicular carcinoma of the kidney presenting in a 13-year-old female: a case report from Syria
title_short Thyroid-like follicular carcinoma of the kidney presenting in a 13-year-old female: a case report from Syria
title_sort thyroid-like follicular carcinoma of the kidney presenting in a 13-year-old female: a case report from syria
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629467/
https://www.ncbi.nlm.nih.gov/pubmed/36348638
http://dx.doi.org/10.1093/jscr/rjac467
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