Intranasal nanoemulsion adjuvanted S-2P vaccine demonstrates protection in hamsters and induces systemic, cell-mediated and mucosal immunity in mice

With the rapid progress made in the development of vaccines to fight the SARS-CoV-2 pandemic, almost >90% of vaccine candidates under development and a 100% of the licensed vaccines are delivered intramuscularly (IM). While these vaccines are highly efficacious against COVID-19 disease, their eff...

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Detalles Bibliográficos
Autores principales: Ganesan, Shyamala, Acosta, Hugo, Brigolin, Chris, Orange, Kallista, Trabbic, Kevin, Chen, Charles, Lien, Chia-En, Lin, Yi-Jiun, Lin, Meei-Yun, Chuang, Ya-Shan, Fattom, Ali, Bitko, Vira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629544/
https://www.ncbi.nlm.nih.gov/pubmed/36322572
http://dx.doi.org/10.1371/journal.pone.0272594

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