MicroRNA Content of Ewing Sarcoma Derived Extracellular Vesicles Leads to Biomarker Potential and Identification of a Previously Undocumented EWS-FLI1 Translocation

Objective: Ewing Sarcoma Family of Tumors (ESFT) are a highly aggressive pediatric bone and soft tissue malignancy with poor outcomes in the refractory and recurrent setting. Over 90% of Ewing Sarcoma (ES) tumors are driven by the pathognomonic EWS-ETS chimeric transcripts and their corresponding on...

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Detalles Bibliográficos
Autores principales: Crow, Jennifer, Samuel, Glenson, Farrow, Emily, Gibson, Margaret, Johnston, Jefferey, Guest, Erin, Miller, Neil, Pei, Dong, Koestler, Devin, Pathak, Harsh, Liang, Xiaobo, Mangels, Cooper, Godwin, Andrew K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629554/
https://www.ncbi.nlm.nih.gov/pubmed/36341281
http://dx.doi.org/10.1177/11772719221132693

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