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Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA

In the wake of the rapid surge in the COVID-19-infected cases seen in Southern and West-Central USA in the period of June-July 2020, there is an urgent need to develop robust, data-driven models to quantify the effect which early reopening had on the infected case count increase. In particular, it i...

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Detalles Bibliográficos
Autores principales: Dandekar, Raj, Wang, Emma, Barbastathis, George, Rackauckas, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629682/
https://www.ncbi.nlm.nih.gov/pubmed/36405358
http://dx.doi.org/10.34133/2021/9798302
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author Dandekar, Raj
Wang, Emma
Barbastathis, George
Rackauckas, Chris
author_facet Dandekar, Raj
Wang, Emma
Barbastathis, George
Rackauckas, Chris
author_sort Dandekar, Raj
collection PubMed
description In the wake of the rapid surge in the COVID-19-infected cases seen in Southern and West-Central USA in the period of June-July 2020, there is an urgent need to develop robust, data-driven models to quantify the effect which early reopening had on the infected case count increase. In particular, it is imperative to address the question: How many infected cases could have been prevented, had the worst affected states not reopened early? To address this question, we have developed a novel COVID-19 model by augmenting the classical SIR epidemiological model with a neural network module. The model decomposes the contribution of quarantine strength to the infection time series, allowing us to quantify the role of quarantine control and the associated reopening policies in the US states which showed a major surge in infections. We show that the upsurge in the infected cases seen in these states is strongly corelated with a drop in the quarantine/lockdown strength diagnosed by our model. Further, our results demonstrate that in the event of a stricter lockdown without early reopening, the number of active infected cases recorded on 14 July could have been reduced by more than 40% in all states considered, with the actual number of infections reduced being more than 100,000 for the states of Florida and Texas. As we continue our fight against COVID-19, our proposed model can be used as a valuable asset to simulate the effect of several reopening strategies on the infected count evolution, for any region under consideration.
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spelling pubmed-96296822022-11-14 Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA Dandekar, Raj Wang, Emma Barbastathis, George Rackauckas, Chris Health Data Sci Research Article In the wake of the rapid surge in the COVID-19-infected cases seen in Southern and West-Central USA in the period of June-July 2020, there is an urgent need to develop robust, data-driven models to quantify the effect which early reopening had on the infected case count increase. In particular, it is imperative to address the question: How many infected cases could have been prevented, had the worst affected states not reopened early? To address this question, we have developed a novel COVID-19 model by augmenting the classical SIR epidemiological model with a neural network module. The model decomposes the contribution of quarantine strength to the infection time series, allowing us to quantify the role of quarantine control and the associated reopening policies in the US states which showed a major surge in infections. We show that the upsurge in the infected cases seen in these states is strongly corelated with a drop in the quarantine/lockdown strength diagnosed by our model. Further, our results demonstrate that in the event of a stricter lockdown without early reopening, the number of active infected cases recorded on 14 July could have been reduced by more than 40% in all states considered, with the actual number of infections reduced being more than 100,000 for the states of Florida and Texas. As we continue our fight against COVID-19, our proposed model can be used as a valuable asset to simulate the effect of several reopening strategies on the infected count evolution, for any region under consideration. AAAS 2021-10-28 /pmc/articles/PMC9629682/ /pubmed/36405358 http://dx.doi.org/10.34133/2021/9798302 Text en Copyright © 2021 Raj Dandekar et al. https://creativecommons.org/licenses/by/4.0/Exclusive Licensee Peking University Health Science Center. Distributed under a Creative Commons Attribution License (CC BY 4.0).
spellingShingle Research Article
Dandekar, Raj
Wang, Emma
Barbastathis, George
Rackauckas, Chris
Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA
title Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA
title_full Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA
title_fullStr Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA
title_full_unstemmed Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA
title_short Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA
title_sort implications of delayed reopening in controlling the covid-19 surge in southern and west-central usa
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629682/
https://www.ncbi.nlm.nih.gov/pubmed/36405358
http://dx.doi.org/10.34133/2021/9798302
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