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A xCT role in tumour-associated ferroptosis shed light on novel therapeutic options

Solute carrier family 7 member 11 (SLC7A11; also known as xCT), a key component of the cystine/glutamate antiporter, is essential for the maintenance of cellular redox status and the regulation of tumor-associated ferroptosis. Accumulating evidence has demonstrated that xCT overexpression, resulting...

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Detalles Bibliográficos
Autores principales: Criscuolo, Daniela, Morra, Francesco, Celetti, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630094/
https://www.ncbi.nlm.nih.gov/pubmed/36338517
http://dx.doi.org/10.37349/etat.2022.00101