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CD8(+) T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging

A hallmark of nervous system aging is a decline of white matter volume and function, but the underlying mechanisms leading to white matter pathology are unknown. In the present study, we found age-related alterations of oligodendrocyte cell state with a reduction in total oligodendrocyte density in...

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Detalles Bibliográficos
Autores principales:	Kaya, Tuğberk, Mattugini, Nicola, Liu, Lu, Ji, Hao, Cantuti-Castelvetri, Ludovico, Wu, Jianping, Schifferer, Martina, Groh, Janos, Martini, Rudolf, Besson-Girard, Simon, Kaji, Seiji, Liesz, Arthur, Gokce, Ozgun, Simons, Mikael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630119/ https://www.ncbi.nlm.nih.gov/pubmed/36280798 http://dx.doi.org/10.1038/s41593-022-01183-6

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