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Adult-born dentate granule cells promote hippocampal population sparsity

The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly, the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan, but their contribution to downstream firing dynamics remains unclear. Here, we show that abDGCs promote sparser hippocam...

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Detalles Bibliográficos
Autores principales: McHugh, Stephen B., Lopes-dos-Santos, Vítor, Gava, Giuseppe P., Hartwich, Katja, Tam, Shu K. E., Bannerman, David M., Dupret, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630129/
https://www.ncbi.nlm.nih.gov/pubmed/36216999
http://dx.doi.org/10.1038/s41593-022-01176-5