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Molecular interactions of FG nucleoporin repeats at high resolution

Proteins that contain repeat phenylalanine-glycine (FG) residues phase separate into oncogenic transcription factor condensates in malignant leukaemias, form the permeability barrier of the nuclear pore complex and mislocalize in neurodegenerative diseases. Insights into the molecular interactions o...

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Detalles Bibliográficos
Autores principales: Ibáñez de Opakua, Alain, Geraets, James A., Frieg, Benedikt, Dienemann, Christian, Savastano, Adriana, Rankovic, Marija, Cima-Omori, Maria-Sol, Schröder, Gunnar F., Zweckstetter, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630130/
https://www.ncbi.nlm.nih.gov/pubmed/36138110
http://dx.doi.org/10.1038/s41557-022-01035-7