HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex

DNA:DNA:RNA triplexes that are formed through Hoogsteen base-pairing of the RNA in the major groove of the DNA duplex have been observed in vitro, but the extent to which these interactions occur in cells and how they impact cellular functions remains elusive. Using a combination of bioinformatic te...

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Detalles Bibliográficos
Autores principales: Leisegang, Matthias S., Bains, Jasleen Kaur, Seredinski, Sandra, Oo, James A., Krause, Nina M., Kuo, Chao-Chung, Günther, Stefan, Sentürk Cetin, Nevcin, Warwick, Timothy, Cao, Can, Boos, Frederike, Izquierdo Ponce, Judit, Haydar, Shaza, Bednarz, Rebecca, Valasarajan, Chanil, Fuhrmann, Dominik C., Preussner, Jens, Looso, Mario, Pullamsetti, Soni S., Schulz, Marcel H., Jonker, Hendrik R. A., Richter, Christian, Rezende, Flávia, Gilsbach, Ralf, Pflüger-Müller, Beatrice, Wittig, Ilka, Grummt, Ingrid, Ribarska, Teodora, Costa, Ivan G., Schwalbe, Harald, Brandes, Ralf P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630315/
https://www.ncbi.nlm.nih.gov/pubmed/36323673
http://dx.doi.org/10.1038/s41467-022-34252-2

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