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Hsp90β inhibition upregulates interferon response and enhances immune checkpoint blockade therapy in murine tumors

Response resistance to the immune checkpoint blockade (ICB) immunotherapy remains a major clinical challenge that may be overcome through the rational combination of ICB and specific targeted therapeutics. One emerging combination strategy is based on sensitizing ICB-refractory tumors with antagonis...

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Detalles Bibliográficos
Autores principales:	Rahmy, Sharif, Mishra, Sanket J., Murphy, Sean, Blagg, Brian S. J., Lu, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630337/ https://www.ncbi.nlm.nih.gov/pubmed/36341371 http://dx.doi.org/10.3389/fimmu.2022.1005045

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