Cargando…

An innovative approach for the evaluation of prolonged disorders of consciousness using NF-L and GFAP biomarkers: a pivotal study

Behavioral assessments during the clinical evaluation in prolonged disorders of consciousness patients could be not sufficient for a correct diagnosis and prognostication. To this aim, we used an innovative approach, involving the ultra-sensitive determination of biological markers, correlating them...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coppola, L., Mirabelli, P., Baldi, D., Smaldone, G., Estraneo, A., Soddu, A., Grimaldi, A. M., Mele, G., Salvatore, Marco, Cavaliere, Carlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630372/ https://www.ncbi.nlm.nih.gov/pubmed/36323711 http://dx.doi.org/10.1038/s41598-022-21930-w

Ejemplares similares

Consciousness and the Dimensionality of DOC Patients via the Generalized Ising Model
por: Abeyasinghe, Pubuditha M., et al.
Publicado: (2020)

Spontaneous eye blinking as a diagnostic marker in prolonged disorders of consciousness
por: Magliacano, Alfonso, et al.
Publicado: (2021)

Multimodal Neuroimaging Approach to Variability of Functional Connectivity in Disorders of Consciousness: A PET/MRI Pilot Study
por: Cavaliere, Carlo, et al.
Publicado: (2018)

Predicting outcome of patients with prolonged disorders of consciousness using machine learning models based on medical complexity
por: Liuzzi, Piergiuseppe, et al.
Publicado: (2022)

Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness
por: Cavaliere, Carlo, et al.
Publicado: (2015)

Plasma NfL and GFAP as biomarkers of spinal cord degeneration in adrenoleukodystrophy
por: van Ballegoij, Wouter J. C., et al.
Publicado: (2020)

Functional Connectivity Substrates for tDCS Response in Minimally Conscious State Patients
por: Cavaliere, Carlo, et al.
Publicado: (2016)

KCTD15 deregulation is associated with alterations of the NF-κB signaling in both pathological and physiological model systems
por: Smaldone, Giovanni, et al.
Publicado: (2021)

GFAP at 50
por: Messing, Albee, et al.
Publicado: (2020)

Predicting Long-Term Recovery of Consciousness in Prolonged Disorders of Consciousness Based on Coma Recovery Scale-Revised Subscores: Validation of a Machine Learning-Based Prognostic Index
por: Magliacano, Alfonso, et al.
Publicado: (2022)

Purification of viable peripheral blood mononuclear cells for biobanking using a robotized liquid handling workstation
por: Coppola, Luigi, et al.
Publicado: (2019)

Behavioral scales variability in patients with prolonged disorders of consciousness
por: Cortese, Maria Daniela, et al.
Publicado: (2023)

Addressing Pain for a Proper Rehabilitation Process in Patients With Severe Disorders of Consciousness
por: Riganello, F., et al.
Publicado: (2021)

Sex Differences in Behavioral Symptoms and the Levels of Circulating GFAP, Tau, and NfL in Patients With Traumatic Brain Injury
por: Sass, Dilorom, et al.
Publicado: (2021)

Minocycline treatment in clinically isolated syndrome and serum NfL, GFAP, and metalloproteinase levels
por: Camara-Lemarroy, Carlos, et al.
Publicado: (2022)

Regulation of GFAP Expression
por: Brenner, Michael, et al.
Publicado: (2021)

Functional networks in prolonged disorders of consciousness
por: Li, Hui, et al.
Publicado: (2023)

Thyrotropic Axis and Disorders of Consciousness in Acquired Brain Injury: A Potential Intriguing Association?
por: Mele, Chiara, et al.
Publicado: (2022)

The neural basis of external responsiveness in prolonged disorders of consciousness
por: Stafford, Clara A., et al.
Publicado: (2019)

GFAPδ/GFAPα ratio directs astrocytoma gene expression towards a more malignant profile
por: Stassen, Oscar M.J.A., et al.
Publicado: (2017)

Management of Epileptic Seizures in Disorders of Consciousness: An International Survey
por: Briand, Marie-Michèle, et al.
Publicado: (2022)

Emergence delirium and postoperative delirium associated with high plasma NfL and GFAP: an observational study
por: Liu, Xingyang, et al.
Publicado: (2023)

Outcomes of Neurorehabilitation Among Patients With Prolonged Disorders of Consciousness
por: Saif, Mohammed, et al.
Publicado: (2023)

Deciding the end of life for patients with disorders of consciousness: a European survey
por: Demertzi, A, et al.
Publicado: (2010)

Serum GFAP and NfL Levels Differentiate Subsequent Progression and Disease Activity in Patients With Progressive Multiple Sclerosis
por: Barro, Christian, et al.
Publicado: (2022)

Sustained Axonal Degeneration in Prolonged Disorders of Consciousness
por: Bagnato, Sergio, et al.
Publicado: (2021)

Neuromodulatory therapies for patients with prolonged disorders of consciousness
por: Wu, Yue-Hao, et al.
Publicado: (2021)

Corrigendum: Functional networks in prolonged disorders of consciousness
por: Li, Hui, et al.
Publicado: (2023)

The efference cascade, consciousness, and its self: naturalizing the first person pivot of action control
por: Merker, Bjorn
Publicado: (2013)

Quantification and prospective evaluation of serum NfL and GFAP as blood-derived biomarkers of outcome in acute ischemic stroke patients
por: Ferrari, Federica, et al.
Publicado: (2023)

Characteristics of Pivotal Trials and FDA Review of Innovative Devices
por: Rising, Joshua P., et al.
Publicado: (2015)

I Feel! Therefore, I Am from Pain to Consciousness in DOC Patients
por: Riganello, Francesco, et al.
Publicado: (2023)

Relationship between consciousness level and perfusion computed tomography in patients with prolonged disorders of consciousness
por: Xiong, Qi, et al.
Publicado: (2022)

KCTD15 Protein Expression in Peripheral Blood and Acute Myeloid Leukemia
por: Smaldone, Giovanni, et al.
Publicado: (2020)

Importance of GFAP isoform‐specific analyses in astrocytoma
por: van Bodegraven, Emma J., et al.
Publicado: (2019)

Increased Expression OF ADAMTS-13, 8-OHdG AND GFAP-NF Correlates with Neuropathology in Feline Infectious Peritonitis Virus-infected Cats
por: Dincel, G.C., et al.
Publicado: (2017)

Neural Plasticity Lessons from Disorders of Consciousness
por: Demertzi, Athena, et al.
Publicado: (2011)

Music in the Treatment of Children and Youth with Prolonged Disorders of Consciousness
por: Pool, Jonathan, et al.
Publicado: (2016)

Prolonged disorders of consciousness: Damaged brains, damaged minds?
por: Keizer, Bert, et al.
Publicado: (2023)

GFAP expression in injured astrocytes in rats
por: Zhang, Shuquan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a1fsb342jmp61713dc4hvla0pb