Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC

The T cell receptor (TCR) expressed by T lymphocytes initiates protective immune responses to pathogens and tumors. To explore the structural basis of how TCR signaling is initiated when the receptor binds to peptide-loaded major histocompatibility complex (pMHC) molecules, we used cryogenic electro...

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Detalles Bibliográficos
Autores principales: Sušac, Lukas, Vuong, Mai T., Thomas, Christoph, von Bülow, Sören, O’Brien-Ball, Caitlin, Santos, Ana Mafalda, Fernandes, Ricardo A., Hummer, Gerhard, Tampé, Robert, Davis, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630439/
https://www.ncbi.nlm.nih.gov/pubmed/35985289
http://dx.doi.org/10.1016/j.cell.2022.07.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630439/
https://www.ncbi.nlm.nih.gov/pubmed/35985289
http://dx.doi.org/10.1016/j.cell.2022.07.010

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