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Phosphorylation of 17β-hydroxysteroid dehydrogenase 13 at serine 33 attenuates nonalcoholic fatty liver disease in mice

17β-hydroxysteroid dehydrogenase-13 is a hepatocyte-specific, lipid droplet-associated protein. A common loss-of-function variant of HSD17B13 (rs72613567: TA) protects patients against non-alcoholic fatty liver disease with underlying mechanism incompletely understood. In the present study, we ident...

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Detalles Bibliográficos
Autores principales: Su, Wen, Wu, Sijin, Yang, Yongliang, Guo, Yanlin, Zhang, Haibo, Su, Jie, Chen, Lei, Mao, Zhuo, Lan, Rongfeng, Cao, Rong, Wang, Chunjiong, Xu, Hu, Zhang, Cong, Li, Sha, Gao, Min, Chen, Xiaocong, Zheng, Zhiyou, Wang, Bing, Liu, Yi’ao, Liu, Zuojun, Wang, Zimei, Liu, Baohua, Fan, Xinmin, Zhang, Xiaoyan, Guan, Youfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630536/
https://www.ncbi.nlm.nih.gov/pubmed/36323699
http://dx.doi.org/10.1038/s41467-022-34299-1