Cargando…

Untargeted metabolomics analysis of the hippocampus and cerebral cortex identified the neuroprotective mechanisms of Bushen Tiansui formula in an aβ(25-35)-induced rat model of Alzheimer’s disease

Background: Bushen Tiansui Formula (BSTSF) is a traditional formulation of Chinese medicine that has been used to treat Alzheimer’s disease (AD) for decades; however, the underlying mechanisms by which this formula achieves such therapeutic effects have yet to be elucidated. Prupose: To investigate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Hongli, Tan, Yejun, Cheng, Xin, Zhang, Zheyu, Huang, Jianhua, Hui, Shan, Zhu, Lemei, Liu, Yuqing, Zhao, Di, Liu, Zhao, Peng, Weijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630565/ https://www.ncbi.nlm.nih.gov/pubmed/36339577 http://dx.doi.org/10.3389/fphar.2022.990307

Ejemplares similares

Integrated Metabolomic and Lipidomic Analysis Reveals the Neuroprotective Mechanisms of Bushen Tiansui Formula in an Aβ1-42-Induced Rat Model of Alzheimer's Disease
por: Yi, Min, et al.
Publicado: (2020)

Bushen-Tiansui Formula Improves Cognitive Functions in an Aβ(1–42) Fibril-Infused Rat Model of Alzheimer's Disease
por: Sheng, Chenxia, et al.
Publicado: (2020)

Protective effects of Bushen Tiansui decoction on hippocampal synapses in a rat model of Alzheimer's disease
por: Hui, Shan, et al.
Publicado: (2017)

Effect of Bushen Tiansui Decoction on Delayed Fracture Healing: A Systematic Review and Meta-analysis
por: Cheng, Ling, et al.
Publicado: (2023)

Anti-Alzheimers molecular mechanism of icariin: insights from gut microbiota, metabolomics, and network pharmacology
por: Liu, Yuqing, et al.
Publicado: (2023)

Ethyl Acetate Extract Components of Bushen-Yizhi Formula Provides Neuroprotection against Scopolamine-induced Cognitive Impairment
por: Zhang, Shi-Jie, et al.
Publicado: (2017)

Author Correction: Ethyl Acetate Extract Components of Bushen-Yizhi Formula Provides Neuroprotection against Scopolamine-induced Cognitive Impairment
por: Zhang, Shi-Jie, et al.
Publicado: (2020)

Mechanisms of the Bushen Huoxue formula in the treatment of osteoarthritis based on network pharmacology-molecular targets
por: Pang, Tingting, et al.
Publicado: (2022)

The Mechanisms of Bushen-Yizhi Formula as a Therapeutic Agent against Alzheimer’s Disease
por: Cai, Haobin, et al.
Publicado: (2018)

A randomized double-blind placebo-controlled multicenter trial of Bushen Yisui and Ziyin Jiangzhuo formula for constipation in Parkinson disease
por: Jin, Zhaohui, et al.
Publicado: (2020)

Effects of Bushen-Yizhi formula on age-related inflammation and oxidative stress in senescence-accelerated mice
por: Hou, Xue-Qin, et al.
Publicado: (2018)

Immunomodulatory Effects of Combination Therapy with Bushen Formula plus Entecavir for Chronic Hepatitis B Patients
por: Ji, Long-Shan, et al.
Publicado: (2019)

Neuroprotective Effects of OMO within the Hippocampus and Cortex in a D-Galactose and Aβ(25–35)-Induced Rat Model of Alzheimer's Disease
por: Deng, Shaodong, et al.
Publicado: (2020)

Therapeutic and Neuroprotective Effects of Bushen Jianpi Decoction on a Rotenone-Induced Rat Model of Parkinson's Disease
por: Liang, Wei, et al.
Publicado: (2022)

Chinese Herbal Medicine Bushen Qinggan Formula for Blood Pressure Variability and Endothelial Injury in Hypertensive Patients: A Randomized Controlled Pilot Clinical Trial
por: Wu, Chunxiao, et al.
Publicado: (2014)

Corrigendum to “Immunomodulatory Effects of Combination Therapy with Bushen Formula plus Entecavir for Chronic Hepatitis B Patients”
por: Ji, Long-Shan, et al.
Publicado: (2022)

Bushen Huoxue formula for the treatment of diminished ovarian reserve: A combined metabolomics and integrated network pharmacology analysis
por: Zeng, Pengfei, et al.
Publicado: (2023)

Bushen-Yizhi formula ameliorates cognition deficits and attenuates oxidative stress-related neuronal apoptosis in scopolamine-induced senescence in mice
por: HOU, XUE-QIN, et al.
Publicado: (2014)

Diabetes mellitus induces a novel inflammatory network involving cancer progression: Insights from bioinformatic analysis and in vitro validation
por: Tan, Yejun, et al.
Publicado: (2023)

Bushen-Yizhi formula ameliorates cognitive dysfunction through SIRT1/ER stress pathway in SAMP8 mice
por: Zhang, Shi-Jie, et al.
Publicado: (2017)

Effect of Jianpi Bushen Sequential Formula on Adjuvant Chemotherapy of Colon Cancer: Study Protocol for a Randomized Controlled Trial
por: Zhang, Tong, et al.
Publicado: (2021)

Bushen-Yizhi Formula Alleviates Neuroinflammation via Inhibiting NLRP3 Inflammasome Activation in a Mouse Model of Parkinson's Disease
por: Mo, Yousheng, et al.
Publicado: (2018)

Correction: Bushen-Yizhi formula ameliorates cognitive dysfunction through SIRT1/ER stress pathway in SAMP8 mice
por: Zhang, Shi-Jie, et al.
Publicado: (2020)

LncRNAs as the Regulators of Brain Function and Therapeutic Targets for Alzheimer’s Disease
por: Liu, Yuqing, et al.
Publicado: (2022)

Non-Coding RNAs as Novel Regulators of Neuroinflammation in Alzheimer’s Disease
por: Liu, Yuqing, et al.
Publicado: (2022)

Bushen Yisui Capsule ameliorates axonal injury in experimental autoimmune encephalomyelitis
por: Fang, Ling, et al.
Publicado: (2013)

Bushen Huoxue Formula Modulates Autophagic Flux and Inhibits Apoptosis to Protect Nucleus Pulposus Cells by Restoring the AMPK/SIRT1 Pathway
por: Gao, Shang, et al.
Publicado: (2022)

Bazi Bushen alleviates skin senescence by orchestrating skin homeostasis in SAMP6 mice
por: Xu, Zhe, et al.
Publicado: (2023)

Effects of bushen qianggu method for primary osteoporosis: A protocol for systematic review and meta-analysis
por: Chen, Guocai, et al.
Publicado: (2020)

Ziyin Bushen Decoction Alleviates Perimenopausal Syndrome in Rats by Enhancing Estradiol Production
por: Tang, Bi-Xin, et al.
Publicado: (2020)

Anti-inflammatory activity of extracts of Bushen-Qiangdu-Zhilv decoction, a Chinese medicinal formula, in M1-polarized RAW264.7
por: Huang, Run-Yue, et al.
Publicado: (2014)

BushenHuoxue formula promotes osteogenic differentiation via affecting Hedgehog signaling pathway in bone marrow stem cells to improve osteoporosis symptoms
por: Chen, Yuqi, et al.
Publicado: (2023)

Computing hubs in the hippocampus and cortex
por: Clawson, Wesley, et al.
Publicado: (2019)

Effect of Bushen Huoxue Prescription on Cognitive Dysfunction of KK-Ay Type 2 Diabetic Mice
por: Zhao, Shao-Yang, et al.
Publicado: (2021)

Bushen Zhuangjin Decoction promotes chondrocyte proliferation by stimulating cell cycle progression
por: LI, XIHAI, et al.
Publicado: (2015)

Treatment effect of Bushen Huayu extract on postmenopausal osteoporosis in vivo
por: OUYANG, LU, et al.
Publicado: (2014)

Bushen-Yizhi formula ameliorates mitochondrial dysfunction and oxidative stress via AMPK/Sirt1 signaling pathway in D-gal-induced aging rats
por: Liao, Yanfang, et al.
Publicado: (2023)

Meta-Analysis of Chinese Traditional Medicine Bushen Huoxue Prescription for Endometriosis Treatment
por: Shan, Jing, et al.
Publicado: (2017)

A Study of the Protective Effect of Bushen Huoxue Prescription on Cerebral Microvascular Endothelia Based on Proteomics and Bioinformatics
por: Zhao, Shao-Yang, et al.
Publicado: (2022)

Bushen Jianpi Formula Combined with Entecavir for the Treatment of HBeAg-Negative Chronic Hepatitis B: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
por: Zhang, Jing-Hao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6ssu8ugs40i1onk7gn1coul1ur