Participation of OCRL1, and APPL1, in the expression, proteolysis, phosphorylation and endosomal trafficking of megalin: Implications for Lowe Syndrome

Megalin/LRP2 is the primary multiligand receptor for the re-absorption of low molecular weight proteins in the proximal renal tubule. Its function is significantly dependent on its endosomal trafficking. Megalin recycling from endosomal compartments is altered in an X-linked disease called Lowe Synd...

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Detalles Bibliográficos
Autores principales: Sandoval, Lisette, Fuentealba, Luz M., Marzolo, María-Paz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630597/
https://www.ncbi.nlm.nih.gov/pubmed/36340038
http://dx.doi.org/10.3389/fcell.2022.911664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630597/
https://www.ncbi.nlm.nih.gov/pubmed/36340038
http://dx.doi.org/10.3389/fcell.2022.911664

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