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IgA(+) memory B-cells are significantly increased in patients with asthma and small airway dysfunction

BACKGROUND: Comprehensive studies investigated the role of T-cells in asthma which led to personalised treatment options targeting severe eosinophilic asthma. However, little is known about the contribution of B-cells to this chronic inflammatory disease. In this study we investigated the contributi...

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Detalles Bibliográficos
Autores principales: Habener, Anika, Grychtol, Ruth, Gaedcke, Svenja, DeLuca, David, Dittrich, Anna-Maria, Happle, Christine, Abdo, Mustafa, Watz, Henrik, Pedersen, Frauke, König, Inke Regina, Thiele, Dominik, Kopp, Matthias Volkmar, von Mutius, Erika, Bahmer, Thomas, Rabe, Klaus Friedrich, Meyer-Bahlburg, Almut, Hansen, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630610/
https://www.ncbi.nlm.nih.gov/pubmed/35595320
http://dx.doi.org/10.1183/13993003.02130-2021