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Metamorphic proteins under a computational microscope: Lessons from a fold-switching RfaH protein
Metamorphic proteins constitute unexpected paradigms of the protein folding problem, as their sequences encode two alternative folds, which reversibly interconvert within biologically relevant timescales to trigger different cellular responses. Once considered a rare aberration, metamorphism may be...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630627/ https://www.ncbi.nlm.nih.gov/pubmed/36382197 http://dx.doi.org/10.1016/j.csbj.2022.10.024 |